Combine chopped chipotle, salt, pepper, lime juice, cilantro, and garlic powder in a large bowl. Stir well. Add ground turkey and mix well with hands. Portion and divide burgers.
Turn on grill or grill pan and coat with non-stick spray. Cook turkey burgers on each side for 2-3 minutes until cooked through.
Assemble burgers by adding mayo, avocado, sliced tomato, and red onion.